Prediction of protein domain boundaries from sequence alone

A description of the method one can find in Protein Science 2003, 12, 696-701 ©

    The program finds the deepest minima in the latent entropy profile. The domain boundary for two-domain protein to be located at the position where the latent entropy profile has its deepest minimum. This minimum is conditioned by amino acid residues with a small value of number of degrees of freedom on the angles φ, ψ and χ (Number of degrees of freedom).
    Some additional explanations can be found here
averaging frame

Target sequence in FASTA format

Report any bug in the prediction service please send to author of electronic design M.Yu.Lobanov

Please cite the prediction server:
Oxana V. Galzitskaya and Bogdan Melnik
“Prediction of protein domain boundaries from sequence alone”
Protein Science. 2003 12:696-701.